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Adverse Drug Reactions are the 4th leading cause of death in the U.S.

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Pain


Are you taking or considering medication to treat or prevent pain?

Are you taking additional medications?

Personalized medication mangement including DNA testing is extremely important for the proper management of pain because finding the right drug and dose is so vitally important. This is not surprising to people that study genetics- research shows that of all the clinical factors such as age, sex, weight, general health and liver function that alter a patient's response to drugs, genetic factors are the most important.

Many common pain medications require activation by an enzyme called CYP2D6 to become effective. Approximately half of patients have genes that alter the function of 2D6. Testing for these gene alterations allows for alteration of dosage regimens to compensate for altered metabolism and optimize the safety and efficacy of the opioid family of analgesics.Without knowing your genetics, your physician may need to go through months of trial-and-error prescribing to find the right drug and dose for you.

Population Frequency of Cytochrome P450 (CYP) Metabolizer Types

  Poor
(no or low enzyme levels)
Intermediate (reduced enzyme levels) Extensive (normal enzyme levels) Ultra-Extensive (high enzyme levels)
CYP2D6 10% 35% 48% 7%

 

Now you can help your healthcare provider optimize your response to cancer drugs and many other medications by ordering DNA testing. Your results will be entered into our personalized medication management software, GeneMedRx You or your healthcare providers can log in to see if current or future medications are predicted to cause drug-drug or drug-gene interactions so dosage and selection can be catered to your needs. You receive a 90-day subscription free with your testing; additional one year extensions are available for a nominal fee. Of course, your DNA never changes so the testing only needs to be done once in a lifetime.

Click here to view a list of drugs for which DNA testing will be helpful.

The Testing Process

The process is simple. You order testing and receive a cheek swab collection kit with directions by mail. Use the return mailer to submit samples and receive results in 10 days or less. Faster testing is available for an additional charge. Call a DNA testing consultant at (800) 523-3080 for details and to order.

Note: Testing is currently not available to New York residents and can only be ordered through a physician in Maryland and California.

 

 


 

Questions? Call us at 1-800-523-3080
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Pharmacogenetic testing can help guide clinical medication management
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What our clients say...

"I just wanted to call and tell you that my physician switched my medications based on my test results, and I cannot describe how much better I feel. You have made a believer out of me, my family, and my physician. I hope this testing becomes routine before anyone is placed on long term medication."
- PY, Eirie, CO