Right Drug. Right Dose. Right Now.
Pharmacogenetic (PGx) testing has the power to reduce adverse drug events (ADEs), improve drug efficacy, and get you to feeling better, faster. Genelex offers a simple, affordable DNA test and provides you with a report that you and your doctor can use to determine which drugs and doses are right for you.
FOR PATIENTS:
More than 90% of the US population has at least one genetic variation that may affect their response to medications. [1]
FOR PROVIDERS:
ADEs are the 4th leading cause of death in hospitalized patients in the US, costing billions of dollars in healthcare.[2]
FOR PHARMACISTS:
Currently, more than 250 medications have PGx information and/or FDA warnings printed on their labels. [3]
FOR CLINICIAL TRIALS:
Genelex offers an unrivaled depth of experience to pharmaceutical companies and other research organizations.
What Patients Are Saying About Genelex:
The Future of Personalized Medicine is Here
With over 30 years of experience in genetic testing, Genelex has the knowledge and expertise to bring you truly personalized medicine.
When it comes to prescribing drugs and evaluating patients for potential drug interactions, pharmacogenetic testing is no longer a future consideration. Leveraging pharmacogenetics to improve drug efficacy is widely accepted in the medical community:
- The American Medical Association advocates that physicians become familiar with genetic variations that can affect patients’ drug metabolism and be able to recognize when testing should be used to inform prescribing.
- The U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada currently require or recommend testing for more than 60 drugs.
- A report from the U.S. Department of Health and Human Services states: “Pharmacogenetic testing for potential ADEs and ineffective drug responses may reduce health care costs over the long term by diminishing the duration and severity of illness and the costs associated with ineffective treatment and avoidable ADEs.”
Genelex is a leader in precision medication management. A pioneer in DNA testing since 1987, Genelex focuses exclusively on pharmacogenetic testing. Backed by a powerful combination of innovative analytics software, state-of-the-art laboratory facilities, and expert staff, Genelex has a longstanding commitment to the prevention of dangerous and life-threatening ADEs.
Each year in the United States, more than 2.2 million ADEs occur, resulting in more than 100,000 deaths and placing an enormous financial burden on the healthcare system. [2] Genelex has been a trailblazer in the area of genetic testing – focused, innovative, and driven to prevent ADEs.
Today, with one simple test, we can improve quality of life and save healthcare resources. At our fingertips, we have access to the tools essential for precision prescribing — allowing for personalizing medication decisions whenever they are made.
Genelex and YouScript®
Genelex pharmacogenetic testing powered by YouScript is the alternative to "one-size-fits-all" drug prescribing.
Genelex, powered by the YouScript Personalized Prescribing software, tests cytochromes (CYPs) and other genes, which are responsible for metabolizing most commonly prescribed medications. Through this partnership, we provide pharmacist-produced reports which tell you how to optimize medications now, and you’ll get access to YouScript analytics software to quickly pick the safest and most effective medications going forward.
Once tested, each patient is classified as a: Poor Metabolizer, Intermediate Metabolizer, Normal Metabolizer, Rapid Metabolizer, or Ultra-rapid Metabolizer. These classifications describe a patient’s inherent drug metabolizing capacity — a major contributor to adverse drug events and adjustments to regimen can be made accordingly.
Genelex DNA pharmacogenetic testing powered by YouScript is the alternative to “one size fits all” drug prescribing that can lead to potentially serious side effects, treatment failure, and poor patient compliance. Pharmacogenetic testing combined with the YouScript Personalized Prescribing software reveals drug-metabolizing gene variants—found in more than 90% of patients—to help physicians and pharmacists determine the appropriateness and dosage of commonly prescribed drugs such as beta blockers, opioid analgesics, statins, and anti-depressants.
Drug sensitivity testing reports include patient-specific information on potential drug-drug, drug-gene, and cumulative interactions mediated by the tested polymorphic drug metabolizing enzymes. The generated reports provide physicians with immediate insight into individual differences in their patients’ drug processing ability and help physicians improve the efficacy and safety of the prescribed treatments. A list of safer alternative drugs is provided.
Pharmacogenetics Basics
Have you ever wondered why a medication works extremely well for some but may have disastrous side effects for others?
Pharmacogenetic testing answers this question and many others. We all have unique, complex genetic characteristics. We typically think of these characteristics as what determines our eye color or whether we are likely to develop certain diseases and disorders. However, genetics also affect how we respond to commonly prescribed medications. This applies not only to prescription medications, but also to over-the-counter medicines, herbal and dietary supplements, and recreational drugs such as marijuana. And, with more than 90%[1] of the population having genetic variations that may impact how we process and metabolize drugs — pharmacogenetics is a critical addition to our healthcare approach
Due to of these genetic differences, two people can take the same dose of the same drug but respond in very different ways. For example, the drug might work very well for one person, but not at all for another. Or the drug might cause side effects for one person, but not for someone else.
In some cases, drug-related side effects can be serious or cause death – even though the drug was prescribed normally by the doctor and used correctly by the patient. People who take several different drugs face an even greater risk of dangerous side effects, especially if they are over 65 years of age.
Now, with a quick DNA test, patients and providers get the insight they need to make informed decisions about their medications and find a treatment that works the first time — with the potentially fewer side effects.