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Home / Patients / Affected Drugs / Strattera

AFFECTED DRUGS: STRATTERA

CYP2D6 Test for Strattera Resistance

Fluorouracil

Plavix

Tamoxifen

Strattera

Warfarin

Additional Drugs

Strattera is a non-stimulant medication known as a norepinephrine reuptake inhibitor used for attention-deficit/hyperactivity disorder (ADD and ADHD). It is commonly prescribed to both children and adults. Although the FDA has approved the drug, the current FDA-approved Strattera label states “Poor metabolizers of CYP2D6 have a 5–fold higher peak concentration to a given dose of Strattera compared with extensive metabolizers." [22]

Strattera is one of many medications processed through pathways in your liver. These pathways vary in their ability to process drugs based on your unique genetic make-up.

About 7% of Caucasians and 1-2% of African-Americans and Asians are poor metabolizers (PMs) of CYP2D6 metabolized drugs. [23]

Like many other pharmaceuticals, individual genetics may play a role in whether an individual will respond to Strattera for ADHD, and whether that individual's particular forms of these genes predispose him or her to require a higher (or lower) than normal dosage level than otherwise similar individuals to achieve the desired effects.

Improving Drug Efficacy

Genelex's pharmacogenetic testing bridges the gap in understanding how the role of PGx can help in patient care and offers a simple DNA test and provides you with a report of the results that you and your doctor can discuss.

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