HIV therapy is known to be associated with a large variability in efficacy and toxicity among different individuals even at standard doses. Reasons for this large inter-individual variability are attributed to race, gender, concomitant medications, drug compliance, underlying diseases, and genetic factors.
Your genes are the main factor determining the level of these enzymes primarily found in your liver — if you have too much of the enzyme, you process the medication too quickly, too little of the enzyme and the medication builds up in your bloodstream potentially causing adverse reactions or side effects.
PGx AND HIV THERAPY
Learn How HIV, Genes, and Drugs Work Together
MedMPact complements current efforts to optimize - personalized care in HIV patients — all while being more cost effective and reducing trial-and-error efforts.
MedMPact includes, drug-drug and drug-gene interaction software, and you'll get a report highlighting patient-specific genetic markers and potential interactions to discuss with your healthcare provider.,
Population Frequency of Cytochrome P450 (CYP) Metabolizer Types 
(no or low enzyme levels)
(reduced enzyme levels)
(normal enzyme levels)
(high enzyme levels)
*CYP2C19 variability depends on ethnicity.
*CYP2D6 Variability depends on ethnicity and classification of Intermediate activity