Millions of Americans currently take acid reflux or ulcer medications.
Your genes are the main factor in determining the level of these enzymes in your liver — if you have too much of the enzyme, you process the medication too quickly, too little of the enzyme and the medication builds up in your bloodstream potentially causing adverse reactions or side effects.
PGx AND ULCERS/ACID REFLUX
Learn How Acid Reflux, Genes, and Drugs Work Together
Over the last decade, significant advancements in pharmacogenetics or “personalized medicine” have provided alternative methods for selecting drugs based on a patient's unique genetic profiles.
MedMPact includes drug-drug and drug-gene interaction software, and you'll get a report highlighting potential interactions to discuss with your healthcare provider.
Population Frequency of Cytochrome P450 (CYP) Metabolizer Types [5]
| Poor (no or low enzyme levels) |
Intermediate(reduced enzyme levels) | Normal (normal enzyme levels) | Rapid or Ultra Rapid Metabolizer(high enzyme levels) | |
|---|---|---|---|---|
| CYP2C9 | 3% | 30% | 68% | N/A |
| CYP2C19* | 2-20% | 24-36% | 14-44% | 30% |
*CYP2C19 variability depends on ethnicity.