Millions of Americans currently take acid reflux or ulcer medications and many have had problems finding the right drug and dose.
Your genes are the main factor in determining the level of these enzymes in your liver — if you have too much of the enzyme, you process the medication too quickly, too little of the enzyme and the medication builds up in your bloodstream potentially causing adverse reactions or side effects.
PGx AND ULCERS/ACID REFLUX
Discover the Right Treatment for Ulcers and Acid Reflux, Faster
Without knowing your genetics, your physician may need to go through months of trial-and-error prescribing to find the right drug and dose for you. However, over the last decade, significant advancements in pharmacogenetics or “personalized medicine” have provided alternative methods for selecting drugs based on a patient's unique genetic profiles. Pharmacogenetics has been successfully used to optimize the selection and dosing of acid reflux medications, as well as helping to avoid adverse effects.
With advances in genetics, you are now able to optimize your response to medications through DNA testing. In partnership with YouScript, a leader in drug-drug and drug-interactions, you'll get a report highlighting potential interactions, allowing for drug and dosage decisions to be catered to your needs.
Population Frequency of Cytochrome P450 (CYP) Metabolizer Types [5]
| Poor (no or low enzyme levels) |
Intermediate(reduced enzyme levels) | Normal (normal enzyme levels) | Rapid or Ultra Rapid Metabolizer(high enzyme levels) | |
|---|---|---|---|---|
| CYP2C9 | 3% | 30% | 68% | N/A |
| CYP2C19* | 2-20% | 24-36% | 14-44% | 30% |
*CYP2C19 variability depends on ethnicity.
Patient Resources
Take a Risk Assessment
Simply enter the medications you’re currently on or plan to take. Click “Get Results” to see if your regimen puts you at risk for an adverse drug reaction.
YOUR GENELEX RISK ASSESSMENT RESULTS: