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Home / Providers / Conditions / Ulcers/Acid Reflux

FOR PATIENTS

Pharmacogenetics and Acid Reflux

Cancer

Depression

Epilepsy

Cardiovascular

Chronic Pain

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Acid Reflux

Millions of Americans currently take acid reflux or ulcer medications.
Over half of all medications including many acid reflux and ulcer medications, such as Prilosec® (omeprazole) and Nexium® (esomeprazole), are metabolized by two enzymes found primarily in the liver called CYP3A4 and CYP2C19.[1,18] 

Population Frequency of Cytochrome P450 (CYP) Metabolizer Types [5]

Poor 
(no or low enzyme levels)
Intermediate(reduced enzyme levels) Normal (normal enzyme levels) Rapid or Ultra Rapid Metabolizer(high enzyme levels)
CYP2C9 3% 30% 68% N/A
CYP2C19* 2-20% 24-36% 14-44% 30%

*CYP2C19 variability depends on ethnicity.

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Pharmacogenetic testing bridges the gap in understanding how the role of PGx can help in patient care and offers a simple DNA test that provides you with a physician report of the patient results to help with optimal care.

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